What are my alternatives to knee replacement?
Compare nonsurgical knee arthritis care, injection choices, and selected surgical alternatives—with evidence, limits, and questions for your clinician.
Read the guide ↗Medically reviewed by Charles A. DeCook, MD ·
← All optionsEstablished care
Topical anti-inflammatory
Rub-on pain relief for the knee.
Who might it suit?
For: Knee pain when an anti-inflammatory is safe for you.
Not for: People with NSAID contraindications; not a first-line treatment for a deep hip joint.
Limits and important cautions
A deep hip joint is less suited to topical treatment. Skin reactions and NSAID contraindications still matter; check other medicines with your clinician.
What happens, how long, and what could it cost?
- What happens
- Review medicines, health conditions, contraindications, and the exact dose with your clinician or pharmacist.
- When might I notice a change?
- Timing depends on the medicine and formulation; follow its label and prescribed plan.
- How long might benefit last?
- Symptom control varies. Ask how long to try it before reviewing the result.
- Repeat treatment
- Review ongoing need and adverse effects. Do not abruptly stop prescribed opioids.
- Activity and recovery
- Ask about driving, interactions, and activities affected by the specific medicine.
- Ask for a complete estimate
- Medicine, visits, and any necessary monitoring.
Use this as a consultation guide. A timeline is not a guarantee; the evidence and FDA sections below remain part of the decision.
THE EVIDENCE IN CONTEXT
Guideline-supported for knee OA
Read the 2 selected references
- ACR/Arthritis Foundation: OA management ↗
2019 guideline, published in 2020. Recommendations vary by joint; it predates many newer trials.
- NICE NG226: osteoarthritis care ↗
UK guidance on exercise, medicines, supports, and referral. Recommendations are not US coverage rules.
FDA status
Approved products · follow the labelApproved diclofenac gel products exist; follow the specific product label.
Site summary of FDA information · reviewed September 19, 2026. Refer to current product labeling. This is not an FDA endorsement of this site.What do professional guidelines say?
AAOS: Strong recommendation for topical NSAIDs for knee OA when not contraindicated.
ACR: Strongly recommends topical NSAIDs for knee OA.
Will Medicare cover it?
Coverage depends on medical need, product, provider, and plan. Confirm before care.